Philosophical

Question 1

The first report of the t8;21 translocation in acute myeloid leukemia was rejected by NEJM.

True/False

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Answer 1

Probably true - see Rowley 1990

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Question 2

Mojica's original report of CRISPER was rejected by Nature.

True/False

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Answer 2

True - see Lander 2016

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Question 3

According to The Philadelphia Chromosome, the first paper reporting the effect of CGP-57148B (imatinib) again BCR-ABL positive cells was rejected by Science and Nature.

True/False

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Answer 3

True - The Philadelphia Chromosome, pg 201

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Question 4

According to Drawing The Map Of Life, Kary Mullis's paper on PCR was rejected by both Nature and Science.

True/False

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Answer 4

True - Drawing The Map Of Life, pg 27

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Question 5

A study leading to the observation of an association between low maternal serum alpha-fetoprotein and fetal chromosomal abnormalities was sparked because of a single case.

True/False

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Answer 5

True - Merkatz et al. PMID: 6201071

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